Shifa Clinical Research Center
Shifa Clinical Research Center envisions leading national and global collaborative efforts in clinical research, aiming for creation of beneficial knowledge (“IlmanNafian”) translating into healing (Shifa) for humanity.
The Shifa Clinical Research Center has set as its mission, facilitating an ethical, scientific and collaborative journey of reflection, inquiry, discovery and innovation
Shifa Clinical Research Center (SCRC) is committed to perform research of highest scientific and ethical standards as reflected in our mission statement. With the guidance of the leadership, all clinical departments are actively involved in research in their respective specialties. Clinical research Center is dedicated to perform and facilitate research in a variety of ways:
- Clinical Research Office
- Cancer Registry
With well-defined research guidelines, our qualified physician investigators and multidisciplinary pool of trained research staff, including medical doctors, pharmacists, Bio- statisticians, tumor registrar and data abstractors offer a unique combination of expertise. The Hospital cancer registry as a part of cancer Control planning, aiming to establish and maintain a cancer incidence reporting system. Cancer registry can ensure the availability of data for treatment, research, education, administration planning and public health decisions.
The SCRC functions in close collaboration with the IRB & EC (Institutional review board and Ethics committee) on various aspects of human and animal research. No Research can be conducted at Shifa International Hospital (SIH), Shifa Tameer-e-Millat University (STMU) and its affiliated institutions without the approval of IRB &EC. The IRB & EC is a wide body which is responsible for policy making, governance, oversight of the ethics review process across shifa and for hearing of appeals.
The Data and safety monitoring board (DSMB) is an independent group of experts that advises Shifa International Hospital. Data and Safety Monitoring Board (DSMB),an independent body responsible for assessing data The primary responsibilities of the DSMB are to 1) periodically review and evaluate the accumulated study data for participant safety, study conduct and progress, and, when appropriate, efficacy, and 2) make recommendations to NIDCR concerning the continuation, modification, or termination of the trial. The DSMB considers study-specific data as well as relevant background knowledge about the disease, test agent, or patient population under study.
Prior to initiating any data review, the DSMB is responsible for defining its deliberative processes, including: event triggers that would call for an unscheduled review, stopping procedures that are consistent with the protocol, unmasking (unblinding), and voting procedures. The DSMB is also responsible for maintaining the confidentiality of its internal discussions and activities as well as the contents of reports provided to it. SCRC playing the leading role in DSMB monitoring.
SCRC is involved in conducting and monitoring of the following parameters:
- Clinical trials
- Post-graduate trainees research core competency programme
SCRC conducts PG trainees reseach programme for fellows of College of Physicians and Surgeons (CPSP), Pakistan (FCPS residents). This program also helps in facilitation of the following services:
- Ethics of clinical research and regulatory issues.
- Research question formulation.
- Research study design
- Synopsis writing.
- Sample size and power calculations.
- Key statistics.
- Dissertation writing
- Proposal submission to IRB & EC
- Research awareness
- Research courses and workshops
The SCRC is promoting clinical research and capacity building in various ways e.g. workshops and training courses.
- Training courses
- Introduction to the principles and practice of clinical research (IPPCR) in collaboration with National institute of health (NIH), Bethesda, Maryland, United States
- Ethical and regulatory aspect of clinical research, National institute of health (NIH), Bethesda, Maryland, United States
- Good clinical practices (GCP), NIH, USA.
- Oral and poster presentation
- Research methodologies
- Research proposal writing
- Scientific Manuscript writing and SPSS
SCRC runs a very vast and extensive program for internship. This gives an excellent opportunity for internees to get familiar with research and its working parameters, ongoing clinical trials, and its working parameters.
Cancer registry in SCRC at SIH shall maintain correct and complete data on all patients diagnosed and/or treated for cancer at SIH. Cancer registry shall establish and maintain a cancer incidence reporting system in SIH.
|Dr. Mian Amjad Sohail|
Director Medical Services/ Shifa Clinical Research Centre
|Dr. Sumeyya Azam|
Senior Clinical Research Associate
|Dr. Ahmed Sohail|
Clinical Research Associate
Zafar Iqbal Armani